2YCP
F448H mutant of tyrosine phenol-lyase from Citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-L-tyrosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | TYROSINE PHENOL-LYASE | polymer | 456 | 51557.8 | 4 | UniProt (P31013) Pfam (PF01212) In PDB | CITROBACTER FREUNDII | BETA-TYROSINASE |
| 2 | D, A, B, C | (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid | non-polymer | 428.3 | 4 | Chemie (P61) | |||
| 3 | A, D, B, C | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 13 | Chemie (PGE) | |||
| 4 | D, A, B | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 5 | Chemie (PG4) | |||
| 5 | C, A | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 6 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | B | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 8 | D, C | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 2 | Chemie (P33) | |||
| 9 | C, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 10 | water | water | 18.0 | 1861 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 456 (UniProt: P31013)
| PDB | External Database | Details |
|---|---|---|
| His 448 | Phe 448 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206231.0 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 5958.3 | |
| All* | Total formula weight | 212189.4 |
