2YAT
Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ESTROGEN RECEPTOR | polymer | 252 | 28773.8 | 1 | UniProt (P03372) Pfam (PF00104) | HOMO SAPIENS (HUMAN) | ESTROGEN RECEPTOR ALPHA, ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP A MEMBER 1 |
| 2 | B (A) | EUROPIUM ION | non-polymer | 152.0 | 1 | Chemie (EU) | |||
| 3 | C (A) | ESTRADIOL-PYRIDINIUM TETRAACETIC ACID | non-polymer | 663.7 | 1 | Chemie (EEU) | |||
| 4 | D, E (A) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 5 | F (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 301 - 551 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Met 300 | - | expression tag |
| Ser 381 | Cys 381 | engineered mutation |
| Ser 417 | Cys 417 | engineered mutation |
| Ser 530 | Cys 530 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28773.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 907.7 | |
| All* | Total formula weight | 29681.5 |
