2YA5
Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with sialic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NEURAMINIDASE A | polymer | 493 | 55346.7 | 2 | UniProt (B2DJD9) Pfam (PF13088) UniProt (by SIFTS) (P62575) In PDB | STREPTOCOCCUS PNEUMONIAE | NANA |
2 | A, B | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 2 | Chemie (SIA) | |||
3 | A, B | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | water | water | 18.0 | 542 | Chemie (HOH) |
Sequence modifications
A, B: 303 - 777 (UniProt: B2DJD9)
PDB | External Database | Details |
---|---|---|
Ala 285 | - | expression tag |
His 286 | - | expression tag |
His 287 | - | expression tag |
His 288 | - | expression tag |
His 289 | - | expression tag |
His 290 | - | expression tag |
His 291 | - | expression tag |
Ser 292 | - | expression tag |
Ser 293 | - | expression tag |
Gly 294 | - | expression tag |
Leu 295 | - | expression tag |
Glu 296 | - | expression tag |
Val 297 | - | expression tag |
Leu 298 | - | expression tag |
Phe 299 | - | expression tag |
Gln 300 | - | expression tag |
Gly 301 | - | expression tag |
Pro 302 | - | expression tag |
Lys 440 | Glu 417 | SEE REMARK 999 |
Asp 584 | Asn 561 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 110693.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 919.6 | |
All* | Total formula weight | 111612.9 |