2Y5F
FACTOR XA - CATION INHIBITOR COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ACTIVATED FACTOR XA HEAVY CHAIN | polymer | 234 | 26419.0 | 1 | UniProt (P00742) Pfam (PF00089) In PDB | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR XA |
| 2 | L | FACTOR X LIGHT CHAIN | polymer | 54 | 5903.6 | 1 | UniProt (P00742) Pfam (PF14670) In PDB | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR XA |
| 3 | A | (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE | non-polymer | 520.1 | 1 | Chemie (XWG) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A: 16 - 244 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Glu 150 | Arg 372 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32322.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 566.0 | |
| All* | Total formula weight | 32888.7 |
