2Y37
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NITRIC OXIDE SYNTHASE, INDUCIBLE | polymer | 433 | 50121.0 | 2 | UniProt (P29477) Pfam (PF02898) In PDB | MUS MUSCULUS (HOUSE MOUSE) | INDUCIBLE NITRIC OXID SYNTHASE, INDUCIBLE NOS, MACROPHAGE NOS, NOS TYPE II, MAC-NOS |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | A, B | 2-[(1R)-3-amino-1-phenyl-propoxy]-4-chloro-benzonitrile | non-polymer | 286.8 | 2 | Chemie (A54) | |||
| 5 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | A, B | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 7 | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100241.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2761.4 | |
| All* | Total formula weight | 103003.3 |
