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2Y1L

Caspase-8 in Complex with DARPin-8.4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CCaspase-8 subunit p18polymer15918027.62UniProt (Q14790)
Pfam (PF00656)
In PDB
Homo sapiens (human)
2B, DCaspase-8polymer10412036.62UniProt (Q14790)
Pfam (PF00656)
In PDB
Homo sapiens (human)CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH
3E, FDARPIN-8.4polymer16918216.52SYNTHETIC CONSTRUCT
4HAC-IETD-CHOpolymer4476.51SYNTHETIC CONSTRUCT
5IN-(2-oxoethyl)-L-isoleucyl-L-alpha-glutamyl-N-[(1R)-2-carboxy-1-formylethyl]-L-threoninamidepolymer5488.51BIRD (PRD_000301)
6A, B, CSULFATE IONnon-polymer96.13Chemie (SO4)
7B, C, E, F1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
8waterwater18.0685Chemie (HOH)
Sequence modifications
A, C: 217 - 374 (UniProt: Q14790)
PDBExternal DatabaseDetails
Met 216-initiating methionine
Gly 217Ser 217conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight97526.3
Non-Polymers*Number of molecules8
Total formula weight598.5
All*Total formula weight98124.8
*Water molecules are not included.

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건을2024-09-18부터공개중

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