2XZ5
MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | SOLUBLE ACETYLCHOLINE RECEPTOR | polymer | 217 | 24674.6 | 5 | UniProt (Q8WSF8) Pfam (PF02931) | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) | ACHBP |
| 2 | F, G, HA, IA, L... (A, E, B, C, D) | ACETYLCHOLINE | non-polymer | 146.2 | 10 | Chemie (ACH) | |||
| 3 | GA, H, JA, N, X (D, A, E, B, C) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 4 | AA, BA, I, J, KA... (D, A, E, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) | |||
| 5 | CA, DA, K, MA, Q... (D, A, E, B, C) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 7 | Chemie (MPD) | |||
| 6 | EA, FA (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | NA, OA, PA, QA, RA (A, B, C, D, E) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 217 (UniProt: Q8WSF8)
| PDB | External Database | Details |
|---|---|---|
| Val 41 | Ala 60 | conflict |
| Sch 53 | Tyr 72 | engineered mutation |
| Val 136 | Ala 155 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 123373.2 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 3858.7 | |
| All* | Total formula weight | 127231.9 |
