2XXX

Crystal structure of the GluK2 (GluR6) D776K LBD dimer in complex with glutamate (P21 21 21)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2	polymer	261	29640.0	4	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2	E, F, G, H (A, B, C, D)	GLUTAMIC ACID	non-polymer		147.1	4	Chemie (GLU)
3	I, J, K, L (A, B, C, D)	water	water		18.0	394	Chemie (HOH)

Sequence modifications

A, B, C, D: 429 - 544 (UniProt: P42260)

PDB	External Database	Details
Gly 428	-	expression tag
Pro 807	-	expression tag
Arg 808	-	expression tag

A, B, C, D: 667 - 806 (UniProt: P42260)

PDB	External Database	Details
Gly 555	-	linker
Thr 566	-	linker
Lys 776	Asp 776	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118560.1
Non-Polymers*	Number of molecules	4
	Total formula weight	588.5
All*	Total formula weight	119148.7

*Water molecules are not included.