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2XXT

Crystal structure of the GluK2 (GluR6) wild-type LBD dimer in complex with kainate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2polymer26129625.92UniProt (P42260)
Pfam (PF10613)
Pfam (PF00060)
RATTUS NORVEGICUS (NORWAY RAT)GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2C, F
(A, B)
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.22Chemie (KAI)
3D, G
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
4E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5H, I
(A, B)
waterwater18.0417Chemie (HOH)
Sequence modifications
A, B: 429 - 544 (UniProt: P42260)
PDBExternal DatabaseDetails
Gly 428-expression tag
Pro 807-expression tag
Arg 808-expression tag
A, B: 667 - 806 (UniProt: P42260)
PDBExternal DatabaseDetails
Gly 555-linker
Thr 566-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59251.9
Non-Polymers*Number of molecules5
Total formula weight507.9
All*Total formula weight59759.8
*Water molecules are not included.

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PDB entries from 2025-07-09

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