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2XX5

Macrolactone Inhibitor bound to HSP90 N-term

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-DEPENDENT MOLECULAR CHAPERONE HSP82polymer21424208.61UniProt (P02829)
Pfam (PF02518)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, HSP90
2B
(A)
(5E,10R)-N-BENZYL-13-CHLORO-14,16-DIHYDROXY-1,11-DIOXO-1,2,3,4,7,8,9,10,11,12-DECAHYDRO-2-BENZAZACYCLOTETRADECINE-10-CARBOXAMIDEnon-polymer470.91Chemie (13N)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.0173Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24208.6
Non-Polymers*Number of molecules2
Total formula weight563.0
All*Total formula weight24771.6
*Water molecules are not included.

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PDB entries from 2025-06-25

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