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2XX2

Macrolactone Inhibitor bound to HSP90 N-term

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-DEPENDENT MOLECULAR CHAPERONE HSP82polymer21424208.64UniProt (P02829)
Pfam (PF02518)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, HSP90
2E, I, J, L
(A, B, C, D)
(5E)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-2-BENZAZACYCLOTETRADECINE-1,11(2H,12H)-DIONEnon-polymer337.84Chemie (13C)
3F, G, H, K
(A, C)
GLYCEROLnon-polymer92.14Chemie (GOL)
4M, N, O, P
(A, B, C, D)
waterwater18.0716Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight96834.3
Non-Polymers*Number of molecules8
Total formula weight1719.6
All*Total formula weight98553.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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