2XWO

SiaP R147E mutant in complex with sialylamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP	polymer	312	35004.5	1	UniProt (P44542) Pfam (PF03480) In PDB	HAEMOPHILUS INFLUENZAE	EXTRACYTOPLASMIC SOLUTE RECEPTOR PROTEIN SIAP, N-ACETYLNEURAMINIC-BINDING PROTEIN, NEU5AC-BINDING PROTEIN, SUBSTRATE BINDING PROTEIN
2	A	(2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxamide	non-polymer		308.3	1	Chemie (SLM)
3		water	water		18.0	389	Chemie (HOH)

Sequence modifications

A: 1 - 306 (UniProt: P44542)

PDB	External Database	Details
Glu 147	Arg 170	engineered mutation
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35004.5
Non-Polymers*	Number of molecules	1
	Total formula weight	308.3
All*	Total formula weight	35312.8

*Water molecules are not included.