2XWC
Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution
Replaces: 2XIPEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TUMOUR PROTEIN P73 | polymer | 208 | 23342.6 | 1 | UniProt (O15350) Pfam (PF00870) | HOMO SAPIENS (HUMAN) | P53-LIKE TRANSCRIPTION FACTOR, P53-RELATED PROTEIN |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 1 | Chemie (TAM) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 112 - 311 (UniProt: O15350)
| PDB | External Database | Details |
|---|---|---|
| Met 111 | - | expression tag |
| Ala 312 | - | expression tag |
| Glu 313 | - | expression tag |
| Asn 314 | - | expression tag |
| Leu 315 | - | expression tag |
| Tyr 316 | - | expression tag |
| Phe 317 | - | expression tag |
| Gln 318 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23342.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 386.1 | |
| All* | Total formula weight | 23728.7 |
