2XV7

Crystal structure of vascular endothelial growth factor D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	VASCULAR ENDOTHELIAL GROWTH FACTOR D	polymer	112	12562.3	1	UniProt (O43915) Pfam (PF00341) In PDB	HOMO SAPIENS (HUMAN)	C-FOS-INDUCED GROWTH FACTOR, VEGF-D, FIGF
2	B, C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
3	A	alpha-D-mannopyranose	non-polymer		180.2	2	Chemie (MAN)
4		water	water		18.0	13	Chemie (HOH)

Sequence modifications

A: 92 - 195 (UniProt: O43915)

PDB	External Database	Details
Asp 90	-	expression tag
Pro 91	-	expression tag
Ala 117	Cys 117	engineered mutation
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	12562.3
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	2
	Total formula weight	360.3
All*	Total formula weight	14095.6

*Water molecules are not included.