2XU0
Crystal structure of the NTS-DBL1(alpha-1) domain of the Plasmodium falciparum membrane protein 1 (PfEMP1) from the varO strain.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ERYTHROCYTE MEMBRANE PROTEIN 1 | polymer | 487 | 56414.0 | 1 | UniProt (B7T1P0) Pfam (PF15447) Pfam (PF05424) Pfam (PF22672) | PLASMODIUM FALCIPARUM PALO ALTO/UGANDA | PLASMODIUM FALCIPARUM MEMBRANE PROTEIN 1 |
| 2 | B (A) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 2 - 487 (UniProt: B7T1P0)
| PDB | External Database | Details |
|---|---|---|
| Phe 1 | - | expression tag |
| Ala 10 | Thr 10 | engineered mutation |
| Ile 66 | Gly 66 | engineered mutation |
| Glu 67 | Tyr 67 | engineered mutation |
| Gly 68 | Val 68 | engineered mutation |
| Ala 125 | Ser 125 | engineered mutation |
| Ala 128 | Thr 128 | engineered mutation |
| Ala 154 | Thr 154 | engineered mutation |
| Ala 186 | Ser 186 | engineered mutation |
| Ala 250 | Ser 250 | engineered mutation |
| Ala 360 | Ser 360 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56414.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 507.8 | |
| All* | Total formula weight | 56921.8 |
