2XS6

CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA	polymer	214	22953.0	1	UniProt (O00459) Pfam (PF00620)	HOMO SAPIENS (HUMAN)	PHOSPHATIDYLINOSITOL 3-KINASE 85 KDA REGULATORY SUBUNIT BETA, PTDINS-3-KINASE REGULATORY SUBUNIT BETA, PI3-KINASE REGULATORY SUBUNIT BETA, PI3K REGULATORY SUBUNIT BETA, PTDINS-3-KINASE REGULATORY SUBUNIT P85-BETA, PI3-KINASE SUBUNIT P85-BETA
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	C (A)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 108 - 298 (UniProt: O00459)

PDB	External Database	Details
Met 85	-	expression tag
His 86	-	expression tag
His 87	-	expression tag
His 88	-	expression tag
His 89	-	expression tag
His 90	-	expression tag
His 91	-	expression tag
Ser 92	-	expression tag
Ser 93	-	expression tag
Gly 94	-	expression tag
Val 95	-	expression tag
Asp 96	-	expression tag
Leu 97	-	expression tag
Gly 98	-	expression tag
Thr 99	-	expression tag
Glu 100	-	expression tag
Asn 101	-	expression tag
Leu 102	-	expression tag
Tyr 103	-	expression tag
Phe 104	-	expression tag
Gln 105	-	expression tag
Ser 106	-	expression tag
Met 107	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22953.0
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	22988.5

*Water molecules are not included.