2XNF
The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | polymer | 159 | 18284.3 | 1 | UniProt (Q71SY5) Pfam (PF11232) | HOMO SAPIENS (HUMAN) | MEDIATOR COMPLEX SUBUNIT 25, ACTIVATOR-RECRUITED COFACTOR 92 KDA COMPONENT, ARC92, ACTIVATOR INTERACTION DOMAIN-CONTAINING PROTEIN 1, P78, MED25 |
Sequence modifications
A: 394 - 543 (UniProt: Q71SY5)
| PDB | External Database | Details |
|---|---|---|
| Met 393 | - | expression tag |
| Leu 544 | - | expression tag |
| Glu 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18284.3 | |
| All* | Total formula weight | 18284.3 |






