2XNB
Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE |
| 2 | B (A) | 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE | non-polymer | 382.5 | 1 | Chemie (Y8L) | |||
| 3 | C (A) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33976.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 382.5 | |
| All* | Total formula weight | 34359.0 |
