2XMY
Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE |
2 | A | 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE | non-polymer | 435.5 | 1 | Chemie (CDK) | |||
3 | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33976.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 435.5 | |
All* | Total formula weight | 34412.0 |