2XJE
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with uridine 5'-monophosphate and adenosine triphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOSOLIC PURINE 5'-NUCLEOTIDASE | polymer | 555 | 64087.9 | 1 | UniProt (P49902) Pfam (PF05761) | HOMO SAPIENS (HUMAN) | CYTOSOLIC 5'-NUCLEOTIDASE II |
| 2 | B (A) | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 1 | Chemie (U5P) | |||
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 1 - 536 (UniProt: P49902)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 52 | Asp 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64087.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 972.1 | |
| All* | Total formula weight | 65060.0 |
