2XJ2
Protein kinase Pim-1 in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1 | polymer | 301 | 34388.9 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | |
| 2 | A | (2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid | non-polymer | 338.4 | 1 | Chemie (985) | |||
| 3 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 14 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34388.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 338.4 | |
| All* | Total formula weight | 34727.3 |
