2XIY
Protein kinase Pim-1 in complex with fragment-2 from crystallographic fragment screen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTO-ONCOGENE SERINE/THREONINE PROTEIN KINASE PIM-1 | polymer | 301 | 34388.9 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | |
| 2 | A | 2-HYDROXYMETHYL-BENZOIMIDAZOLE | non-polymer | 148.2 | 1 | Chemie (XIY) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 14 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34388.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 353.8 | |
| All* | Total formula weight | 34742.8 |
