2XHU

HCV-J4 NS5B Polymerase Orthorhombic Crystal Form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RNA-directed RNA polymerase	polymer	579	64599.0	2	UniProt (O92972) Pfam (PF00998)	Hepatitis C virus genotype 1b (strain HC-J4) (HCV)	NS5B,p68
2	C, D, E, F, G... (A, B)	SULFATE ION	non-polymer		96.1	17	Chemie (SO4)
3	T, U (A, B)	water	water		18.0	727	Chemie (HOH)

Sequence modifications

A, B: 1 - 570 (UniProt: O92972)

PDB	External Database	Details
Ala 0	-	expression tag
Leu 571	-	expression tag
Glu 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	129198.0
Non-Polymers*	Number of molecules	17
	Total formula weight	1633.1
All*	Total formula weight	130831.0

*Water molecules are not included.