2XGD

Crystal structure of a designed homodimeric variant T-A(L)A(L) of the tetracycline repressor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D	polymer	208	23486.7	1	UniProt (P04483) UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909)	ESCHERICHIA COLI
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	C (A)	water	water		18.0	55	Chemie (HOH)

Sequence modifications

A: 1 - 50 (UniProt: P04483)
A: 51 - 208 (UniProt: P0ACT4)

PDB	External Database	Details
Trp 136	Ala 136	engineered mutation
Ile 197	Phe 197	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23486.7
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	23522.2

*Water molecules are not included.