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2XEY

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SERINE/THREONINE-PROTEIN KINASE CHK1polymer28933043.01UniProt (O14757)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)CHECKPOINT KINASE 1, CHEK1, CHK1
2B
(A)
3-(1H-INDOL-3-YL)-6-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINEnon-polymer300.31Chemie (YVQ)
3C
(A)
waterwater18.011Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33043.0
Non-Polymers*Number of molecules1
Total formula weight300.3
All*Total formula weight33343.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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