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2XDG

Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
GROWTH HORMONE-RELEASING HORMONE RECEPTORpolymer9210026.22UniProt (Q02643)
Pfam (PF02793)
HOMO SAPIENS (HUMAN)GHRH RECEPTOR, GROWTH HORMONE-RELEASING FACTOR GRF RECEPTOR, GRFR
2C, E, F
(A, B)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
3D, G
(A, B)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4H, I
(A, B)
waterwater18.083Chemie (HOH)
Sequence modifications
A, B: 34 - 123 (UniProt: Q02643)
PDBExternal DatabaseDetails
Ser -1-expression tag
Met 0-expression tag
Gln 50Asn 50engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight20052.4
Non-Polymers*Number of molecules5
Total formula weight197.1
All*Total formula weight20249.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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