2XCH
Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1 | polymer | 309 | 35427.6 | 1 | UniProt (O15530) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | HPDK1 |
| 2 | B (A) | 8-(CYCLOHEXA-2,5-DIEN-1-YLIDENEAMINO)-1-(PIPERIDIN-4-YLMETHYL)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE | non-polymer | 403.5 | 1 | Chemie (CKG) | |||
| 3 | C, D, E, F, G... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | I, J, K, L, M... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | O (A) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35427.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1532.4 | |
| All* | Total formula weight | 36960.0 |
