2XBJ
Crystal Structure of Chk2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE CHK2 | polymer | 329 | 37111.8 | 1 | UniProt (O96017) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 2, CDS1 |
| 2 | B (A) | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL | non-polymer | 442.5 | 1 | Chemie (XBJ) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 5 | F (A) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37111.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 590.8 | |
| All* | Total formula weight | 37702.6 |
