2XB6
Revisited crystal structure of Neurexin1beta-Neuroligin4 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NEUROLIGIN-4, X-LINKED | polymer | 588 | 66230.2 | 2 | UniProt (Q8N0W4) Pfam (PF00135) | HOMO SAPIENS (HUMAN) | NEUROLIGIN-4, NEUROLIGIN X, HNLX |
| 2 | C, D (C, D) | NEUREXIN-1-BETA | polymer | 179 | 19367.7 | 2 | UniProt (Q63373) Pfam (PF02210) | RATTUS NORVEGICUS (RAT) | NEUREXIN I-BETA |
| 3 | E, F, S, T (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | AA, BA, CA, DA, EA... (B, A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 30 | Chemie (EDO) | |||
| 5 | IA, JA, KA, Q, R (B, A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | LA (C) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 7 | SA, TA (C, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | UA, VA, WA, XA (A, B, C, D) | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 619 (UniProt: Q8N0W4)
| PDB | External Database | Details |
|---|---|---|
| Asp -12 | - | expression tag |
| Tyr -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Arg 561 | Lys 561 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 171195.8 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 3199.5 | |
| All* | Total formula weight | 174395.4 |
