2XB6

Revisited crystal structure of Neurexin1beta-Neuroligin4 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NEUROLIGIN-4, X-LINKED	polymer	588	66230.2	2	UniProt (Q8N0W4) Pfam (PF00135) In PDB	HOMO SAPIENS (HUMAN)	NEUROLIGIN-4, NEUROLIGIN X, HNLX
2	C, D	NEUREXIN-1-BETA	polymer	179	19367.7	2	UniProt (Q63373) Pfam (PF02210) In PDB	RATTUS NORVEGICUS (RAT)	NEUREXIN I-BETA
3	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
4	B, A, C	1,2-ETHANEDIOL	non-polymer		62.1	30	Chemie (EDO)
5	B, A	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
6	C	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
7	C, D	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8		water	water		18.0	349	Chemie (HOH)

Sequence modifications

A, B: 44 - 619 (UniProt: Q8N0W4)

PDB	External Database	Details
Asp -12	-	expression tag
Tyr -11	-	expression tag
Lys -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Lys -5	-	expression tag
Leu -4	-	expression tag
Ala -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Arg 561	Lys 561	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	171195.8
Non-Polymers*	Number of molecules	42
	Total formula weight	3199.5
All*	Total formula weight	174395.4

*Water molecules are not included.