2XAQ
Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 | polymer | 852 | 93011.5 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) In PDB | HOMO SAPIENS | LYSINE-SPECIFIC HISTONE DEMETHYLASE LSD1, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2, BRAF35-HDAC COMPLEX PROTEIN BHC110 |
| 2 | B | REST COREPRESSOR 1 | polymer | 482 | 53102.0 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) In PDB | HOMO SAPIENS | COREPRESSOR COREST, PROTEIN COREST |
| 3 | A | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 4 | A | 3-{4-[(PHENYLCARBONYL)AMINO]PHENYL}PROPANOIC ACID | non-polymer | 269.3 | 1 | Chemie (M84) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146113.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1054.8 | |
| All* | Total formula weight | 147168.3 |
