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2XAH

Crystal structure of LSD1-CoREST in complex with (+)-trans-2- phenylcyclopropyl-1-amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LYSINE-SPECIFIC HISTONE DEMETHYLASE 1polymer85293011.51UniProt (O60341)
Pfam (PF04433)
Pfam (PF01593)
HOMO SAPIENSLYSINE-SPECIFIC HISTONE DEMETHYLASE LSD1, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2, BRAF35-HDAC COMPLEX PROTEIN BHC110
2B
(B)
REST COREPRESSOR 1polymer48253102.01UniProt (Q9UKL0)
Pfam (PF01448)
Pfam (PF00249)
Pfam (PF20878)
HOMO SAPIENSCOREPRESSOR COREST, PROTEIN COREST
3C
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
4D
(A)
3-PHENYLPROPANALnon-polymer134.21Chemie (3PL)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight146113.4
Non-Polymers*Number of molecules2
Total formula weight919.7
All*Total formula weight147033.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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