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2X7C

Crystal structure of human kinesin Eg5 in complex with (S)-enastron

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
KINESIN-LIKE PROTEIN KIF11polymer36841055.62UniProt (P52732)
Pfam (PF00225)
HOMO SAPIENS (HUMAN)KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, KINESIN-LIKE PROTEIN 1, TRIP-5
2C, F
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3D, G, H
(A, B)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4E, I
(A, B)
(S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAHYDROQUINAZOLIN-5(6H)-ONEnon-polymer274.32Chemie (KZ9)
5J, K
(A, B)
waterwater18.0683Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82111.2
Non-Polymers*Number of molecules7
Total formula weight1476.0
All*Total formula weight83587.2
*Water molecules are not included.

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PDB entries from 2024-10-30

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