2X7C
Crystal structure of human kinesin Eg5 in complex with (S)-enastron
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 2 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, KINESIN-LIKE PROTEIN 1, TRIP-5 |
2 | C, F (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
3 | D, G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
4 | E, I (A, B) | (S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAHYDROQUINAZOLIN-5(6H)-ONE | non-polymer | 274.3 | 2 | Chemie (KZ9) | |||
5 | J, K (A, B) | water | water | 18.0 | 683 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 82111.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1476.0 | |
All* | Total formula weight | 83587.2 |