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2X6I

THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-90

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPHOSPHOTIDYLINOSITOL 3 KINASE 59Fpolymer69678765.52UniProt (Q9W1M7)
Pfam (PF00613)
Pfam (PF00454)
In PDB
DROSOPHILA MELANOGASTER (FRUIT FLY)GH13170P, VPS34
2A, BN-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDEnon-polymer350.42Chemie (090)
Sequence modifications
A, B: 258 - 949 (UniProt: Q9W1M7)
PDBExternal DatabaseDetails
Gly 254-expression tag
Ser 255-expression tag
His 256-expression tag
Met 257-expression tag
Ala 455Gly 455engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight157530.9
Non-Polymers*Number of molecules2
Total formula weight700.7
All*Total formula weight158231.6
*Water molecules are not included.

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PDB entries from 2024-07-17

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