2X6I
THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-90
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PHOSPHOTIDYLINOSITOL 3 KINASE 59F | polymer | 696 | 78765.5 | 2 | UniProt (Q9W1M7) Pfam (PF00613) Pfam (PF00454) | DROSOPHILA MELANOGASTER (FRUIT FLY) | GH13170P, VPS34 |
| 2 | C, D (A, B) | N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE | non-polymer | 350.4 | 2 | Chemie (090) |
Sequence modifications
A, B: 258 - 949 (UniProt: Q9W1M7)
| PDB | External Database | Details |
|---|---|---|
| Gly 254 | - | expression tag |
| Ser 255 | - | expression tag |
| His 256 | - | expression tag |
| Met 257 | - | expression tag |
| Ala 455 | Gly 455 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 157530.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 700.7 | |
| All* | Total formula weight | 158231.6 |
