2X6D
Aurora-A bound to an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE 6 | polymer | 285 | 32948.8 | 1 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | AURORA-A, AURORA KINASE A, SERINE/THREONINE-PROTEIN KINASE AURORA-A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, ARK-1, HARK-1, BREAST TUMOR-AMPLIFIED KINASE |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 6-BROMO-7-[4-(4-CHLOROBENZYL)PIPERAZIN-1-YL]-2-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]-3H-IMIDAZO[4,5-B]PYRIDINE | non-polymer | 581.9 | 1 | Chemie (X6D) | |||
| 4 | E (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 122 - 403 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | - | expression tag |
| Ala 120 | - | expression tag |
| Met 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32948.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 774.1 | |
| All* | Total formula weight | 33722.8 |
