2X4O

Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 envelope peptide env120-128

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN	polymer	275	31854.2	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439)	HOMO SAPIENS (HUMAN)	MHC CLASS I ANTIGEN A*2
2	B, E (B, E)	BETA-2-MICROGLOBULIN	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	HOMO SAPIENS (HUMAN)
3	C, F (C, F)	ENVELOPE GLYCOPROTEIN GP160	polymer	9	988.3	2	UniProt (P04583)	HUMAN IMMUNODEFICIENCY VIRUS 1	ENV POLYPROTEIN
4	G, K, L, M, O... (A, D, E)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5	H, I, J, N (B, D, E)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	4	Chemie (MES)
6	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	417	Chemie (HOH)

Sequence modifications

B, E: 0 - 0 (PDB: 2X4O)
B, E: 1 - 99 (UniProt: P61769)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	89443.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1333.5
All*	Total formula weight	90777.2

*Water molecules are not included.