2X4N

Crystal structure of MHC CLass I HLA-A2.1 bound to residual fragments of a photocleavable peptide that is cleaved upon UV-light treatment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN	polymer	275	31854.2	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439)	HOMO SAPIENS (HUMAN)	MHC CLASS I ANTIGEN A*2
2	B, E (B, E)	BETA-2-MICROGLOBULIN	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	HOMO SAPIENS (HUMAN)
3	C, F (C, F)	HLA-A2.1-RESTRICTED INFLUENZA A MATRIX EPITOPE	polymer	9	1146.3	2		INFLUENZA A VIRUS
4	G, H, I, J, L... (A, B, D, E)	GLYCEROL	non-polymer		92.1	10	Chemie (GOL)
5	K, P (D, E)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
6	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	235	Chemie (HOH)

Sequence modifications

B, E: 0 - 0 (PDB: 2X4N)
B, E: 1 - 99 (UniProt: P61769)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	89759.7
Non-Polymers*	Number of molecules	12
	Total formula weight	1311.4
All*	Total formula weight	91071.2

*Water molecules are not included.