2X39

Structure of 4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo(2,3-d)pyrimidin- 4-yl)piperidine-4-carboxamide bound to PKB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RAC-BETA SERINE/THREONINE-PROTEIN KINASE	polymer	342	39860.4	1	UniProt (P31751) Pfam (PF00069) Pfam (PF00433) In PDB	HOMO SAPIENS (HUMAN)	RAC-PK-BETA, PROTEIN KINASE AKT-2, PROTEIN KINASE B\,BETA, PKB BETA
2	C	GLYCOGEN SYNTHASE KINASE-3 BETA	polymer	10	1123.2	1	UniProt (P49841) In PDB	HOMO SAPIENS	GSK-3 BETA, GSK-3 BETA
3	A	4-AMINO-N-(4-CHLOROBENZYL)-1-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE	non-polymer		384.9	1	Chemie (X39)
4		water	water		18.0	246	Chemie (HOH)

Sequence modifications

A: 141 - 145 (PDB: 2X39)
A: 465 - 479 (PDB: 2X39)
A: 146 - 464 (UniProt: P31751)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40983.6
Non-Polymers*	Number of molecules	1
	Total formula weight	384.9
All*	Total formula weight	41368.5

*Water molecules are not included.