2X2R
Crystal structure of human kinesin Eg5 in complex with (R)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 3 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, KINESIN-LIKE PROTEIN 1, TRIP-5 |
| 2 | D, G, J (A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 3 | E, H, K (A, B, C) | (2R)-2-AMINO-3-[(2R)-2-METHYL-1,1-DIPHENYL-BUTYL]SULFANYL-PROPANOIC ACID | non-polymer | 343.5 | 3 | Chemie (X2O) | |||
| 4 | F, I, L (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | M, N, O (A, B, C) | water | water | 18.0 | 737 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123166.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2385.0 | |
| All* | Total formula weight | 125551.7 |
