2X2M
Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | polymer | 314 | 35788.2 | 2 | UniProt (P07949) Pfam (PF07714) In PDB | HOMO SAPIENS (HUMAN) | RET TYROSINE KINASE RECEPTOR, C-RET |
2 | A, B | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
3 | A, B | (3Z)-3-[(3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE | non-polymer | 238.3 | 2 | Chemie (X2M) | |||
4 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 71576.4 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 706.7 | |
All* | Total formula weight | 72283.1 |