2X1N
Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design
Replaces: 2WHAEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE |
2 | B, D | CYCLIN-A2 | polymer | 261 | 29966.6 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN-A |
3 | H | ACE-LEU-ASN-PFF-NH2 | polymer | 5 | 434.5 | 1 | SYNTHETIC CONSTRUCT | ||
4 | A, C | 2-METHYL-N-[(1Z)-3-NITROCYCLOHEXA-2,4-DIEN-1-YLIDENE]-4,5-DIHYDRO[1,3]THIAZOLO[4,5-H]QUINAZOLIN-8-AMINE | non-polymer | 339.4 | 2 | Chemie (X1N) | |||
5 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 128320.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 678.7 | |
All* | Total formula weight | 128999.5 |