2WZ6
G93A SOD1 mutant complexed with Quinazoline.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, F) | SUPEROXIDE DISMUTASE [CU-ZN] | polymer | 153 | 15841.6 | 2 | UniProt (P00441) Pfam (PF00080) | HOMO SAPIENS (HUMAN) | |
| 2 | C, E, J, K (A, F) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | D, I (A, F) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 4 | F, M (A, F) | 4-(4-METHYL-1,4-DIAZEPAN-1-YL)-2-(TRIFLUOROMETHYL)QUINAZOLINE | non-polymer | 310.3 | 2 | Chemie (ZO0) | |||
| 5 | G, H, L (A, F) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | N, O (A, F) | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence modifications
A, F: 1 - 153 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Ala 93 | Gly 94 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31683.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1297.6 | |
| All* | Total formula weight | 32980.7 |
