2WY3
Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE B | polymer | 319 | 36278.7 | 2 | UniProt (Q29980) Pfam (PF00129) Pfam (PF07654) In PDB | HOMO SAPIENS (HUMAN) | MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE B ALLELE 002, MIC-B |
| 2 | B, D | UNCHARACTERIZED PROTEIN UL16 | polymer | 158 | 17735.1 | 2 | UniProt (P16757) Pfam (PF17622) In PDB | HUMAN HERPESVIRUS 5 STRAIN AD169 | UL16 |
| 3 | A, C, D | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL | non-polymer | 1221.5 | 3 | Chemie (PEU) | |||
| 4 | A, B, C | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 6 | water | water | 18.0 | 639 | Chemie (HOH) |
Sequence modifications
A, C: 0 - 0 (PDB: 2WY3)
A, C: 1 - 318 (UniProt: Q29980)
A, C: 1 - 318 (UniProt: Q29980)
| PDB | External Database | Details |
|---|---|---|
| Glu 57 | Lys 80 | conflict |
| Asn 113 | Asp 136 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 108027.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 6496.0 | |
| All* | Total formula weight | 114523.5 |
