2WXN
The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL07.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | polymer | 940 | 107823.7 | 1 | UniProt (Q3UDT3) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O35904) | MUS MUSCULUS (HOUSE MOUSE) | PI3-KINASE P110 SUBUNIT DELTA, PTDINS-3-KINASE P110, P110DELTA, PI3K |
| 2 | B (A) | 3-{[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl}phenol | non-polymer | 293.3 | 1 | Chemie (DLN) | |||
| 3 | C (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 106 - 1044 (UniProt: Q3UDT3)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107823.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 293.3 | |
| All* | Total formula weight | 108117.0 |
