2WXH
The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW14.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | polymer | 940 | 107823.7 | 1 | UniProt (Q3UDT3) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O35904) In PDB | MUS MUSCULUS (MOUSE) | PI3-KINASE P110 SUBUNIT DELTA, PTDINS-3-KINASE P110, P110DELTA, PI3K |
2 | A | 2-{[4-amino-3-(3-fluoro-4-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one | non-polymer | 507.5 | 1 | Chemie (ZZO) | |||
3 | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 107823.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 507.5 | |
All* | Total formula weight | 108331.2 |