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2WWF

Plasmodium falciparum thymidylate kinase in complex with TMP and ADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
THYMIDILATE KINASE, PUTATIVEpolymer21224950.33UniProt (Q8I4S1)
Pfam (PF02223)
PLASMODIUM FALCIPARUM
2D, L, T
(A, B, C)
THYMIDINE-5'-PHOSPHATEnon-polymer322.23Chemie (TMP)
3E, M, U
(A, B, C)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.23Chemie (ADP)
4F, G, K, N, O...
(A, B, C)
SODIUM IONnon-polymer23.07Chemie (NA)
5H, I, J, P, Q...
(A, B, C)
GLYCEROLnon-polymer92.19Chemie (GOL)
6AA, BA, Z
(B, C, A)
waterwater18.0489Chemie (HOH)
Sequence modifications
A, B, C: 1 - 210 (UniProt: Q8I4S1)
PDBExternal DatabaseDetails
Ser -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight74851.0
Non-Polymers*Number of molecules22
Total formula weight3238.0
All*Total formula weight78089.0
*Water molecules are not included.

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PDB entries from 2025-10-08

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