2WUC
Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp and Ac-KQLR-chloromethylketone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HEPATOCYTE GROWTH FACTOR ACTIVATOR LONG CHAIN | polymer | 257 | 27982.6 | 1 | UniProt (Q04756) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | |
| 2 | B (B) | HEPATOCYTE GROWTH FACTOR ACTIVATOR SHORT CHAIN | polymer | 35 | 3962.7 | 1 | UniProt (Q04756) | HOMO SAPIENS (HUMAN) | |
| 3 | C (H) | FAB FRAGMENT FAB40.DELTATRP HEAVY CHAIN | polymer | 224 | 23584.4 | 1 | HOMO SAPIENS (HUMAN) | ||
| 4 | D (I) | ACE-KQLR-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 606.2 | 1 | BIRD (PRD_000307) | SYNTHETIC CONSTRUCT | |
| 5 | E (L) | FAB FRAGMENT FAB40.DELTATRP LIGHT CHAIN | polymer | 214 | 23238.7 | 1 | HOMO SAPIENS (HUMAN) | ||
| 6 | F (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | G, H, I, J, K (A, B, H, I, L) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 79374.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| All* | Total formula weight | 79799.0 |
