2WS7
Semi-synthetic analogue of human insulin ProB26-DTI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | INSULIN A CHAIN | polymer | 21 | 2383.7 | 6 | UniProt (P01308) | HOMO SAPIENS | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | INSULIN B CHAIN | polymer | 26 | 2939.4 | 6 | UniProt (P01308) | HOMO SAPIENS | |
| 3 | M, P, S, T, U... (A, C, E, G, I...) | PHENOL | non-polymer | 94.1 | 6 | Chemie (IPH) | |||
| 4 | N, Q (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | O, R (B, D) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | AA, BA, CA, DA, EA... (E, F, G, H, I...) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
B, D, F, H, J, L: 1 - 26 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Pro 26 | Tyr 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 31938.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 766.4 | |
| All* | Total formula weight | 32704.9 |
