2WRX
Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | INSULIN A CHAIN | polymer | 21 | 2383.7 | 2 | UniProt (P01308) In PDB | HOMO SAPIENS | |
| 2 | B, D | INSULIN B CHAIN | polymer | 30 | 3355.9 | 2 | UniProt (P01308) Pfam (PF00049) In PDB | HOMO SAPIENS | |
| 3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Maa 26 | Tyr 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 11479.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 11502.2 |
