2WRU
Semi-synthetic highly active analogue of human insulin NMeAlaB26-DTI- NH2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INSULIN A CHAIN | polymer | 21 | 2383.7 | 1 | UniProt (P01308) | HOMO SAPIENS | |
| 2 | B (B) | INSULIN B CHAIN | polymer | 26 | 2926.4 | 1 | UniProt (P01308) | HOMO SAPIENS | |
| 3 | C, D (B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
B: 1 - 26 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Zzj 26 | Tyr 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5310.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 118.1 | |
| All* | Total formula weight | 5428.2 |
