2WPU
Chaperoned ruthenium metallodrugs that recognize telomeric DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | STREPTAVIDIN | polymer | 159 | 16570.0 | 1 | UniProt (P22629) Pfam (PF01382) In PDB | STREPTOMYCES AVIDINII | BIOTIN-BINDING PROTEIN |
2 | A | (3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III) | non-polymer | 598.2 | 1 | Chemie (KYT) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 14 - 159 (UniProt: P22629)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Ala 2 | - | expression tag |
Ser 3 | - | expression tag |
Met 4 | - | expression tag |
Thr 5 | - | expression tag |
Gly 6 | - | expression tag |
Gly 7 | - | expression tag |
Gln 8 | - | expression tag |
Gln 9 | - | expression tag |
Met 10 | - | expression tag |
Gly 11 | - | expression tag |
Arg 12 | - | expression tag |
Asp 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16570.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 786.3 | |
All* | Total formula weight | 17356.4 |